Readers ask: What Antibiotic Irreversibly Inhibits Bacterial Protein Synthesis Quizlet?


Which antibiotics block bacterial protein production quizlet?

The best known of the antibiotics that block bacterial protein synthesis (Table 2.2) target either the small ribosomal subunit (tetracyclines and aminoglycosides) or the large subunit (erythromycins, streptogramins, and lincosamide).

Which antibiotics inhibit bacterial protein synthesis?

Erythromycin, roxithromycin, and clarithromycin all prevent elongation at the transpeptidation step of synthesis by blocking the 50S polypeptide export tunnel.

Which of these antibiotics inhibits protein synthesis quizlet?

How does tetracycline inhibit protein synthesis? Tetracycline interferes with the attachment of tRNA to the mRNA-ribosome complex.

Which antibiotic does not inhibit protein synthesis?

In this class are chloramphenicol, erythromycin, and the tetracyclines. Several other antibiotics of previously unknown mode of action are in this class. A fourth group of substances had no effect on M protein synthesis.

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What process is affected by antibiotics?

Antibiotics disrupt essential processes or structures in the bacterial cell. This either kills the bacterium or slows down bacterial growth. Depending on these effects an antibiotic is said to be bactericidal or bacteriostatic.

Which antibiotic binds to 30S ribosomes to prevent protein synthesis in bacteria quizlet?

AMINOGLYCOSIDES bind to the 30S ribosome and freeze the initiation complex.

Do antibiotics disrupt protein synthesis?

Antibiotics that bind the A-site, such as the aminoglycosides, interfere with codon recognition and translocation. Peptide bond formation is inhibited when small molecules like oxazolidinones bind at the PTC. Finally, macrolides tend to block the growth of the amino acid chain at the peptide exit tunnel.

Are examples of drugs that inhibit protein synthesis?

The following are the medications that are protein synthesis inhibitors.

  • Aminoglycosides.
  • Tetracycline and glycylcycline.
  • Oxazolidinones.
  • Amphenicols and pleuromutilins.
  • Macrolides and ketolides.
  • Lincosamides.
  • Streptogramins.

How will you target protein synthesis using antibiotics?

It is reported that many clinically used antibiotics specifically target bacterial ribosomes [151], targeting different stages of bacterial protein synthesis based on their binding site in the ribosome or by binding to other protein factors associated with protein biosynthesis.

Which of the following antibiotics attacks the ribosome and prevents protein synthesis?

The macrolides, such as erythromycin, are thought to inhibit protein synthesis by binding to the 50S subunit and blocking the tunnel where the polypeptide string is supposed to exit. This clogs up the ribosome and stops translation.

Which of the following antibiotics inhibits mycolic acid synthesis?

Which antimicrobial works by inhibiting the synthesis of mycolic acid? explanation: Isoniazid (INH) is a very effective synthetic antimicrobial drug against Mycobacterium tuberculosis. The primary effect of INH is to inhibit the synthesis of mycolic acids, which are components of cell walls only of the mycobacteria.

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Which of the following antibiotics inhibits RNA synthesis?

We learned about two major classes of antibiotics, the rifamycins and the quinolones and fluoroquinolones. Rifamycins inhibit the bacterial RNA polymerase, preventing transcription, and they are special because they can penetrate well into cells and tissues.

Why do bacteria need protein synthesis?

Bacteria use proteins for many purposes: structure, as enzymes, or for transport. Protein synthesis takes several steps working together. Antibiotics that prevent protein synthesis are used to cure bacterial infections.

Can inhibit the process of protein synthesis?

A protein synthesis inhibitor is a substance that stops or slows the growth or proliferation of cells by disrupting the processes that lead directly to the generation of new proteins. It usually refers to substances, such as antimicrobial drugs, that act at the ribosome level.

What are the different inhibitors of protein synthesis?

Protein synthesis inhibitors include sordarins which selectively inhibit fungal protein synthesis by blocking the function of elongation factor 2 (EF-2) and ribosomes. They are absent in human cells. Sphingolipid biosynthesis inhibitors are also being currently investigated to identify new antifungal targets.

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