Quick Answer: Which Of The Following Antimicrobials Is A Broad Spectrum Antibiotic That Targets The Ribosome?

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Which antibiotic is a broad spectrum drug?

Examples of broad – spectrum antibiotics Doxycycline. Minocycline. Aminoglycosides (except for streptomycin) Ampicillin.

What antibiotics target bacterial ribosomes?

Different antibiotic classes target different ribosomal subunits. Aminoglycosides and tetracyclines, for example, target the 30S subunit, while oxazolidinones, macrolides, ketolides, streptogramins, phenyl propanoids, lincosamides and thiazolo peptides, among others, target the 50S ribosomal subunit.

What are broad spectrum antibiotics target?

Narrow – spectrum and broad – spectrum antibiotics Antibiotics can either have a narrow or broad spectrum of activity. Narrow – spectrum antibiotics are more specific and only active against certain groups or strains of bacteria. Broad – spectrum antibiotics instead inhibit a wider range of bacteria.

Which antimicrobial drug has the broadest spectrum of activity?

The aminoglycosides, which include drugs such as streptomycin, gentamicin, neomycin, and kanamycin, are potent broad- spectrum antibacterials.

What is best broad spectrum antibiotic?

Ciprofloxacin. Best use of this new broad – spectrum antibiotic.

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Is kanamycin a broad spectrum antibiotic?

Kanamycin A is similar to streptomycin and neomycines, and it possesses a broad spectrum of antimicrobial action. It is active with respect to most Gram-positive and Gram-negative microorganisms (staphylococci, colon bacillus, klebisella, Fridlender’s bacillus, proteus, shigella, salmonella).

Do antibiotics target the ribosome?

The ribosome is a major bacterial target for antibiotics. Drugs inhibit ribosome function either by interfering in messenger RNA translation or by blocking the formation of peptide bonds at the peptidyl transferase centre. These effects are the consequence of the binding of drugs to the ribosomal subunits.

What antibiotics does Target translate to?

A: Streptomycin, spectinomycin and tetracycline target bacterial 16S rRNA; puromycin resembles the 3′ end of the aminoacylated tRNA. B: Lincomycin, clindamycin, and chloramphenicol target bacterial 23S rRNA; mupirocin targets aminoacyl tRNA synthetase.

Why do antibiotics that target bacterial ribosomes not make humans sick?

Human cells do not make or need peptidoglycan. Penicillin, one of the first antibiotics to be used widely, prevents the final cross-linking step, or transpeptidation, in assembly of this macromolecule. The result is a very fragile cell wall that bursts, killing the bacterium.

Are broad spectrum antibiotics bad?

Broad – spectrum antibiotics can lead to a dangerous form of diarrhea, called “C. diff.” It can require removal of the bowel. It kills about 15,000 people in the U.S. each year. Antibiotics can also cause other side effects, such as vaginal infections, nausea, and vomiting.

What is the difference between a broad spectrum and narrow-spectrum antibiotic?

Narrow – spectrum antibiotics target a few types of bacteria. Broad – spectrum antibiotics target many types of bacteria. Both types work well to treat infections. But using broad – spectrum antibiotics when they’re not needed can create antibiotic -resistant bacteria that are hard to treat.

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Is doxycycline a broad spectrum antibiotic?

Background: Doxycycline is an broad – spectrum antimicrobial agent, it remains an inexpensive alternative for the treatment of community-acquired respiratory infections and urinary tract infections.

What are the five main classes of antimicrobial drugs?

Antimicrobial agents are classified into several categories, i.e. inhibitors for bacterial cell wall such as beta-lactam drugs, fosfomycin, and vancomycin; inhibitors for protein biosynthesis such as tetracyclibnes, macrolides, aminoglycoside antibiotics; inhibitors for DNA synthesis such as 4-quinolones; inhibitors

Why was penicillin considered a miracle drug?

Penicillin was hailed as a ” miracle drug ” that could save lives and effectively treat a variety of infectious diseases. Today, there are many natural and synthetic types of penicillin, which are used to treat a wide range of ailments.

Which organism is most sensitive to natural penicillin?

The natural penicillins have activity against non-beta-lactamase producing gram-positive cocci, including viridans streptococci, group A streptococci, Streptococcus pneumoniae, and anaerobic streptococcus (Peptostreptococcus, Peptococcus sp.). Enterococcus sp. is most susceptible to the natural penicillins.

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